20% Albumin

A 20% albumin solution may reduce the total crystalloid volume needed during high-fluid-demand surgery. The article states that albumin efficacy in major non-cardiac surgery with high fluid requirements has not been sufficiently evaluated. Albumin is the main binding and transport protein in plasma and the principal determinant of vascular oncotic pressure. Known risks of 20% human albumin include rare immunoallergic reactions, infrequent cardiovascular events, and possible renal impairment.