4-Vinylguaiacol

4-Vinylguaiacol supports immune function and produces systemic anti-inflammatory action via Nrf2 activation. 4-Vinylguaiacol is considered indirectly more powerful than a simple exogenous antioxidant because it upregulates the body's own antioxidant defenses. 4-Vinylguaiacol is a phenolic compound that is generated or concentrated during the heating of turmeric. 4-Vinylguaiacol activates the Nrf2 transcription factor, which is central to the body's endogenous antioxidant defense. Nrf2 activation from 4-vinylguaiacol upregulates production of endogenous antioxidant enzymes including glutathione and superoxide dismutase.