ACE2 Receptors
Diabetics have significantly more ACE2 receptor proteins expressed on their cells than healthy individuals. Once SARS-CoV-2 binds to an ACE2 receptor, the virus enters the cell and begins replicating. Both elevated blood glucose and elevat…
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Diabetics have significantly more ACE2 receptor proteins expressed on their cells than healthy individuals. Once SARS-CoV-2 binds to an ACE2 receptor, the virus enters the cell and begins replicating. Both elevated blood glucose and elevated insulin levels independently increase ACE2 receptor expression, and both conditions are present simultaneously in type 2 diabetes. Higher ACE2 receptor density on cells directly increases a person's susceptibility to infection.