Active and Sham Light Intervention
Active BLT is intended to target melanopsin cells, while sham BLT uses a yellowish low-intensity spectrum to avoid melanopsin activation. Participants complete 30-minute morning light sessions on waking for 14 consecutive days. Both trial…
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Active BLT is intended to target melanopsin cells, while sham BLT uses a yellowish low-intensity spectrum to avoid melanopsin activation. Participants complete 30-minute morning light sessions on waking for 14 consecutive days. Both trial groups wear the same DAYVIA SUNACTIV 2 light therapy glasses. The light therapy device is contraindicated only in specific ophthalmic conditions including retinopathy, retinitis pigmentosa, diabetic retinopathy, macular degeneration, and glaucoma. Prior safety data showed similar side-effect rates between active and sham BLT and no serious adverse events.