Advanced Endometriosis

Endometriosis is described as a chronic inflammatory oestrogen-dependent disease involving endometrial-like cells outside the uterus. Fertility impairment in endometriosis can involve adhesions, distorted anatomy, diminished ovarian reserve, and inflammatory or immunological effects on implantation. Endometriosis commonly causes pain symptoms, gastrointestinal and urinary symptoms, and infertility. Women with endometriosis have reduced spontaneous conception rates and about a twofold higher infertility risk than women without endometriosis.