Aging and Degenerative Disease

The brain is affected by these degenerative forces earlier and more severely than the rest of the body. Degenerative disease is driven by two interacting problems: free radical damage and a decline in energy production. CoQ10 production begins declining around age 20, with conversion to the active form also diminishing after age 35. Neurons are especially vulnerable because they require continuous energy for signaling, damage repair, and protection from oxidative stress.