ALPPS

ALPPS had significantly greater FLR gain than two-stage hepatectomy with PVEfLR in a Scandinavian multicentre randomised controlled trial. ALPPS achieves larger and faster standardised FLR increases than PVEfLR. Median overall survival differences between ALPPS and PVEfLR across studies were not statistically significant. In-hospital mortality rates were not significantly different between PVEfLR and ALPPS. ALPPS complication rates are substantially higher than PVEfLR and the comprehensive complication index is significantly higher. ALPPS is sometimes used as salvage therapy when patients fail to progress to resection after PVE.