Androgen Deprivation Therapy

ADT-related sarcopenic obesity combines lower muscle mass, strength, and function with excess body fat. ADT improves survival in advanced prostate cancer but is linked to multiple adverse effects. ADT-related adverse effects include weight…

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ADT-related sarcopenic obesity combines lower muscle mass, strength, and function with excess body fat. ADT improves survival in advanced prostate cancer but is linked to multiple adverse effects. ADT-related adverse effects include weight gain, muscle loss, sarcopenic obesity, diabetes risk, and cardiovascular disease risk. ADT-related changes are associated with a 10-45% increased risk of comorbidities.