Antimicrobial Stewardship

Several stewardship-related indicators improved from 2020 to 2023 despite persistently high antibiotic use. The trial hypothesizes that a kinetics-based approach will safely reduce unjustified antibiotic treatments. In Uganda, a stewardship programme in six hospitals reduced unnecessary antibiotic use for upper respiratory tract infections and reduced antibiotics per patient for urinary tract infections. Antimicrobial stewardship was especially important because treatment durations were prolonged and watch and reserve antibiotics were used substantially. Strengthening evidence for empirical amoxicillin use in CAP could support the UN target for 70% of human antibiotic consumption to come from Access antibiotics by 2030. Wound culture swabs can identify significant organisms and guide antimicrobial susceptibility testing, enabling narrower, targeted antibiotic therapy instead of broad-spectrum prescribing. PCT protocols in acute respiratory infections may produce savings by reducing unnecessary antibiotic use. Ceftriaxone, a Watch antibiotic, was universally available, while benzylpenicillin, an Access antibiotic, was absent. The review focuses on diagnostic stewardship outside ant…