Arginine

L-arginine stimulates the release of growth hormone. Unlike most protein sources, arginine does not meaningfully raise blood glucose or insulin, making it compatible with a fasted state. Unlike most protein sources, arginine does not meaningfully raise blood glucose or insulin, so it can stimulate growth hormone without disrupting a fasted state. Taking arginine before exercise on an empty stomach maximizes its effect on growth hormone pulsatility. The recommended dosage of L-arginine is 3 grams taken twice daily on an empty stomach. Doses of 5–9 g of arginine produce approximately a 100% increase in GH. Arginine at 5–9 g produces approximately a 100% increase in growth hormone. Among individual amino acids, arginine has the strongest evidence for stimulating growth hormone. Arginine has the strongest evidence among individual amino acids for boosting GH. Clinical doses of approximately 2.2 g/day of arginine produced measurable height increases in children with short stature. L-arginine is an amino acid whose biochemical breakdown releases nitric oxide. Arginine's primary mechanism is inhibition of somatostatin, the hormone that suppresses growth hormone release. By blocking somat…