BASE Protocol
The protocol recommends 500 mg of berberine twice daily with the two largest meals. The protocol recommends an eight-week minimum trial period, with 12 weeks preferred. The protocol pairs berberine with a 10- to 15-minute walk within 30 mi…
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The protocol recommends 500 mg of berberine twice daily with the two largest meals. The protocol recommends an eight-week minimum trial period, with 12 weeks preferred. The protocol pairs berberine with a 10- to 15-minute walk within 30 minutes after meals. The ecosystem component emphasizes polyphenols and arabinoxylan-rich fiber to support Akkermansia and SCFA-producing bacteria. The schedule component recommends a consistent noon-to-8 eating window to support gut rhythms and microbiome effects. The BASE protocol combines berberine dosing, movement, meal timing, and gut ecosystem support.