Beta-Blocker Therapy
Esmolol is considered suitable for unstable acute aortic syndromes because it has rapid onset, short half-life, easy titration, and organ-independent metabolism. Reducing heart rate and myocardial contractility lowers blood pressure, after…
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Esmolol is considered suitable for unstable acute aortic syndromes because it has rapid onset, short half-life, easy titration, and organ-independent metabolism. Reducing heart rate and myocardial contractility lowers blood pressure, afterload, myocardial oxygen consumption, and dP/dt. Beta-blockers are the core pharmacological strategy before surgery because they reduce heart rate and myocardial contractility.