Biomarker Measurement

The biomarker panel may change depending on detectability and current research. Skin autofluorescence is measured at baseline as a non-invasive estimate of AGE accumulation. SASP and ageing biomarkers are analysed using BioPlex 200 and sel…

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The biomarker panel may change depending on detectability and current research. Skin autofluorescence is measured at baseline as a non-invasive estimate of AGE accumulation. SASP and ageing biomarkers are analysed using BioPlex 200 and selected ELISAs. A 5 mL venous blood sample is collected at baseline and serum is stored at -80°C in the ICU biorepository.