Brain Glucose Metabolism
The brain consumes 20% of all available fuel in the body despite comprising only 2% of total body tissue. When glucose metabolism falters in the brain, oxygen utilization drops correspondingly because oxygen is used almost entirely to oxid…
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The brain consumes 20% of all available fuel in the body despite comprising only 2% of total body tissue. When glucose metabolism falters in the brain, oxygen utilization drops correspondingly because oxygen is used almost entirely to oxidize glucose. When brain glucose delivery or absorption fails even partially, neurons begin to atrophy and die. The cerebral metabolic rate of glucose can be measured to detect Alzheimer's dysfunction before symptoms appear.