Cardiac Function Biomarkers
Secondary endpoints were not significantly different between CDR132L and placebo. Grade 1 was defined by LVEF of at least 55%. LVEF declined progressively across grades from Grade 1 to Grade 4. LVEF is widely used for longer-term prognosis…
2 sources - 11 claims
Secondary endpoints were not significantly different between CDR132L and placebo. Grade 1 was defined by LVEF of at least 55%. LVEF declined progressively across grades from Grade 1 to Grade 4. LVEF is widely used for longer-term prognosis but has limitations because it does not fully capture hemodynamics or post-STEMI remodeling. Patients with EF below 30% were classified as Grade 4 because they likely have extensive post-infarction damage and a prognosis similar to patients with moderate EF reduction plus severe remodeling.