Central Neuroplasticity
Motor threshold is treated as a direct measure of corticomotor excitability. No randomized controlled trials had tested intensive upper limb motor training on cortical excitability in sub-acute cervical spinal cord injury. The trial assess…
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Motor threshold is treated as a direct measure of corticomotor excitability. No randomized controlled trials had tested intensive upper limb motor training on cortical excitability in sub-acute cervical spinal cord injury. The trial assesses central neuroplasticity mainly with TMS measures of corticospinal tract excitability and integrity. The primary central endpoint is resting motor threshold at a 200 microvolt target motor-evoked potential. TMS is described as an established method for assessing corticospinal tract neuroplasticity through motor-evoked potentials.