Central Serous Chorioretinopathy

Central serous chorioretinopathy is a macular disease involving serous fluid accumulation beneath the neurosensory retina. The pathophysiology of CSC involves choroidal hyperpermeability. CSC commonly causes central scotoma, metamorphopsia, and micropsia. CSC predominantly affects middle-aged men in high-stress occupations. Chronic CSC can cause irreversible retinal pigment epithelium damage. A long-term observational study found that 12.8% of chronic CSC patients became legally blind over a mean follow-up of 11.3 years. CSC can progress to pachychoroid neovascularisation.