Cerebral Autoregulation

MAPopt is defined as the MAP at the lowest point of the autoregulation curve. Cerebral autoregulation maintains cerebral blood flow despite changes in perfusion pressure. PRECISION measures cerebral haemodynamic insults by both magnitude and duration of MAP deviations from personalised cerebral autoregulation thresholds. When MAP is within the autoregulation range, cerebral blood flow is relatively independent of MAP. MAP below the lower limit of autoregulation may produce pressure-passive perfusion and hypoperfusion. MAP above the upper limit of autoregulation may produce hyperperfusion.