Challenge Strain FA1090

The target delivered dose is about 1.0 x 10^6 colony forming units and is expected to infect about 80% of inoculated participants. Before inoculation, bacteria are selected for a predominantly piliated, Opacity protein-negative phenotype e…

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The target delivered dose is about 1.0 x 10^6 colony forming units and is expected to infect about 80% of inoculated participants. Before inoculation, bacteria are selected for a predominantly piliated, Opacity protein-negative phenotype expressing the lacto-N-neotetraose LOS epitope. The study uses N. gonorrhoeae strain FA1090 variant A26 for challenge.