Chronic Disease Progression

Stroke is described as brain bleeding from arterial rupture that kills cells in the affected region. Heart disease is described as gradual functional-stage degeneration involving inflammation, cholesterol production, plaque accumulation, and narrowing vessels. Atherosclerosis is presented as vessel narrowing that reduces blood delivery while the heart continues functioning under poor supply. Addison's disease is described as near-complete or complete adrenal function loss that can lead to total physiological shutdown under minor stressors. Arterial loss of elasticity and structural integrity is said to make arteries vulnerable to rupture.