Clade IIa
One Sierra Leone genome belonged to clade IIa rather than clade IIb. The Sierra Leone clade IIa genome clustered with two Guinea clade IIa genomes from 2024. The clade IIa phylogenetic context supports historical circulation of clade IIa i…
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One Sierra Leone genome belonged to clade IIa rather than clade IIb. The Sierra Leone clade IIa genome clustered with two Guinea clade IIa genomes from 2024. The clade IIa phylogenetic context supports historical circulation of clade IIa in West Africa. The data could not distinguish importation from Guinea from an independent zoonotic event in Sierra Leone for the clade IIa case. Scarce APOBEC3 substitutions in recent clade IIa sequences support zoonotic spillover rather than sustained human transmission.