Clinical Trial Underrepresentation in Africa
Africa is increasingly positioned as an emerging destination for clinical research. Low- and middle-income countries, especially in Africa, account for fewer than 3% of the world's clinical trials despite carrying the largest global diseas…
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Africa is increasingly positioned as an emerging destination for clinical research. Low- and middle-income countries, especially in Africa, account for fewer than 3% of the world's clinical trials despite carrying the largest global disease burden. Africa's clinical research environment has historically been labelled 'not conducive' to clinical investigation, with insufficient human resources and limited commercial viability as root causes. Early research phases in Africa are often conducted elsewhere, disconnected from local health contexts. The creation of the African Medicines Agency and regional harmonisation initiatives are gradually unlocking the continent's research potential.