Comorbidities and Vaccination

Booster vaccination suggested possible benefit, but interpretation was limited by confounding and missing data. Sinovac first, second, or two-dose vaccination was associated with higher category 4 prevalence than BNT162b2 or ChAdOx1 nCoV-19. Hypertension may worsen COVID-19 through inflammatory, immune, cardiovascular, blood-flow, oxygenation, and metabolic pathways. Hypertension and chronic kidney disease were the only comorbidities with statistically significant differences across severity categories. Vaccination status was associated with severity category. All analysed hospitalised patients had at least one pre-existing condition.