Continuous Diagnostic Tests

The hybrid model can estimate sensitivity and false positive fraction curves across observed thresholds for continuous tests. Many diagnostic tests are continuous biomarkers whose clinical classification depends on thresholds. Continuous t…

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The hybrid model can estimate sensitivity and false positive fraction curves across observed thresholds for continuous tests. Many diagnostic tests are continuous biomarkers whose clinical classification depends on thresholds. Continuous tests reported at multiple thresholds can be represented as conditional binomial counts across ordered thresholds. Thresholded continuous test results have a monotonic nested structure as thresholds change.