COVID-19 Antibody Testing

COVID-19 antibody tests detect the immune system's response to prior infection, not active infection. A person can simultaneously have a positive PCR test for active viral shedding and a positive antibody test; antibody positivity does not…

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COVID-19 antibody tests detect the immune system's response to prior infection, not active infection. A person can simultaneously have a positive PCR test for active viral shedding and a positive antibody test; antibody positivity does not preclude transmitting the virus. In low-prevalence settings, even a high-specificity antibody test generates a substantial proportion of false positive results.