COVID-19 Thrombosis

No published consensus protocol exists for when to escalate COVID-19 patients to therapeutic anticoagulation doses. An autopsy series found nine times the normal number of micro-clots in the pulmonary vasculature of COVID-19 decedents. D-d…

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No published consensus protocol exists for when to escalate COVID-19 patients to therapeutic anticoagulation doses. An autopsy series found nine times the normal number of micro-clots in the pulmonary vasculature of COVID-19 decedents. D-dimer values in severe COVID-19 can reach 35 mg/L, which is 70 times the upper limit of normal. COVID-19 produces a hypercoagulable state significantly beyond typical hospital-acquired thrombosis risk. Supplemental vitamin K is counterproductive for COVID-19 patients concerned about clot risk because it pushes the coagulation system toward hypercoagulability.