Culture Expansion and Viability

The article criticizes marketing that reports stem cell products by milliliters or total nucleated cells instead of live MSC counts. The article treats live mesenchymal stem cell counts and viability as more meaningful than product volume or total nucleated cell count. Culture expansion is the laboratory process of feeding stem cells specialized media so they replicate and increase in number. The described laboratory process uses an FDA-registered, inspected, current good manufacturing practice facility with sterile clean rooms. The article says culture expansion can increase a small starting number of cells into quantities that may reach billions.