Cytoreductive Surgery with HIPEC

CRS with HIPEC creates major intraoperative fluid shifts because of surgical resection, peritoneal inflammation, and increased capillary permeability. Both intraoperative hypovolemia and volume overload are associated with poor postoperati…

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CRS with HIPEC creates major intraoperative fluid shifts because of surgical resection, peritoneal inflammation, and increased capillary permeability. Both intraoperative hypovolemia and volume overload are associated with poor postoperative outcomes in this setting. CRS combined with HIPEC is described as the established standard of care for peritoneal metastases from gastrointestinal and gynaecological cancers and mesothelioma.