Diagnosis and Under-recognition

Only 3% of patients who present to a doctor with fatigue receive any diagnosis at all. The 3% fatigue diagnosis rate is statistically equivalent to a random person receiving a random diagnosis. Adult screening tools such as Wells criteria, Geneva score, PERC, and D-dimer testing have not been sufficiently validated in children. The gap between clinical incidence and autopsy prevalence supports concern that paediatric PTE is under-recognised. Women with fatigue are particularly likely to be told their exhaustion stems from the demands of motherhood and multitasking.