Digitalis Trials
DIGIT-HF found a significant 15% reduction in all-cause death plus first heart failure admission with low-dose digitoxin. DIGIT-HF enrolled a more advanced heart failure population than DECISION. RATE-AF found similar quality-of-life effec…
1 sources - 5 claims
DIGIT-HF found a significant 15% reduction in all-cause death plus first heart failure admission with low-dose digitoxin. DIGIT-HF enrolled a more advanced heart failure population than DECISION. RATE-AF found similar quality-of-life effects for low-dose digoxin and bisoprolol, while digoxin performed better on several heart failure-related endpoints. DECISION should be interpreted together with DIG and DIGIT-HF. The DIG trial found no all-cause mortality reduction from digoxin but did reduce hospitalization for worsening heart failure.