Diverticulitis

The pathogenesis of diverticular disease is multifactorial and not fully understood. Diverticular disease involves herniation of colonic mucosa and submucosa through the muscular wall. Approximately 20–55% of people who develop diverticuli…

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The pathogenesis of diverticular disease is multifactorial and not fully understood. Diverticular disease involves herniation of colonic mucosa and submucosa through the muscular wall. Approximately 20–55% of people who develop diverticulitis experience recurrent episodes. An estimated 5–25% of people with diverticulosis develop diverticulitis at least once. Recurrent diverticulitis can lead to repeat hospitalisation, invasive intervention, chronic pain, reduced productivity, and lower quality of life.