DNA Methylation Aging Clocks

DNA methylation is emphasized for aging clocks because it is stable, technically mature, widely measurable across tissues, and strongly correlated with aging. The provided text does not include mechanisms, studies, recommendations, or actionable insights about epigenetic clocks. Classical epigenetic clocks such as Horvath use elastic net regression to select age-associated CpG sites and predict age. DNA methylation aging clocks estimate biological age from molecular biomarkers. The source material identifies epigenetic clocks as a topic related to aging rate prediction. The source material links biological clocks to health risk assessment.