DOOR Ranking

The DOOR hierarchy ranks survival as the most important outcome. Return to pre-infection functional level is the second priority in the DOOR hierarchy. The primary outcome is a patient-centred DOOR hierarchical composite endpoint assessed…

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The DOOR hierarchy ranks survival as the most important outcome. Return to pre-infection functional level is the second priority in the DOOR hierarchy. The primary outcome is a patient-centred DOOR hierarchical composite endpoint assessed at day 90. Complications form the third DOOR component because patient representatives considered culture results and persistent, relapsing, or new infection highly relevant.