Drug-Coated Balloon Type
The SPACIOUS trial found sirolimus-coated balloons non-inferior to paclitaxel-coated balloons for side branch treatment when combined with main-vessel DES. Paclitaxel's high lipophilicity allows rapid drug transfer after short exposure. Si…
1 sources - 4 claims
The SPACIOUS trial found sirolimus-coated balloons non-inferior to paclitaxel-coated balloons for side branch treatment when combined with main-vessel DES. Paclitaxel's high lipophilicity allows rapid drug transfer after short exposure. Sirolimus has delivery challenges but may provide sustained antiproliferative effects. Most drug-coated balloons used in the included studies were paclitaxel-coated.