DUTCH Hormone Panel

Saliva testing captures the bioavailable free hormone fraction and diurnal rhythm data that serum and urine tests cannot provide. The DUTCH panel assesses 35 hormones and neurotransmitters, providing context for how nitric oxide deficiency manifests beyond purely vascular symptoms. Impaired nitric oxide production can depress central modulators of sexual behavior and mood by disrupting oxytocin release in the brain. The DUTCH test with cycle mapping is particularly suited for PCOS workup because it provides multiple simultaneous data layers. In men with erectile dysfunction, the DUTCH panel helps distinguish between low testosterone, vascular impairment, or a combination as the underlying cause. For patients without a regular cycle, a synthetic calendar cycle allows the DUTCH map to reveal whether progesterone peaks appropriately in the luteal phase.