EDI-OCT

All successful EDI-OCT scans achieved excellent image quality, with a mean Q-score of 38.9. Compared with sublingual sidestream-dark field microscopy, OCT offers precise spatial registration across time and can detect micron-scale anatomical changes, making it potentially useful for repeated microvascular assessment. OCT angiography could provide complementary or superior information about choroidal vascularity but could only be performed in 56% of patients in a prior study due to its longer acquisition time. The Spectralis Flex setup required two or three operators and cooperation from the bedside multidisciplinary team. EDI-OCT imaging of the choroid is feasible and safe in ICU and high-dependency patients requiring Level 2 or Level 3 care. Baseline EDI-OCT imaging succeeded in 86% of the patients in whom it was attempted. Median EDI-OCT image acquisition time was 2 minutes.