Endogenous Erythritol

The study did not measure how much erythritol participants actually consumed from food or supplements. The body produces erythritol as a byproduct of glucose metabolism. Endogenous erythritol is elevated in diabetics, people with liver or kidney disease, oxidative stress, and visceral fat, all of which independently drive cardiovascular risk. Elevated blood erythritol may be a biomarker of metabolic dysfunction rather than the mechanism causing cardiovascular risk. Elevated blood erythritol in study participants was likely produced by the body rather than consumed through diet.