Epigenetics

Lifestyle, nutrition, environmental management, and mental attitude are the dominant factors controlling gene expression. Retinal reprogramming in old mice has restored eyesight in research described by the article. Stress-driven gene expression changes are reversible because changing lifestyle inputs changes the gene expression outputs. Exercise has documented effects on gene expression that can counteract the influence of high-risk genetic variants. Epigenetic measurements provide a longer-term biological window than proteomic or metabolomic markers. Neither diet nor drugs replicate the combined effect of these epigenetic levers. Ninety to ninety-five percent of whether a person develops disease or stays healthy is determined by epigenetics rather than inherited genes. Suicidal behaviour heritability is estimated at 30% to 50% based on twin and family studies. The notion that a person is predestined to certain diseases because of their genetic inheritance is not supported by the science of epigenetics. Pre-conception SNP testing for MTHFR, COMT, and MTRR combined with targeted nutrient optimization has been associated with substantially below-average ASD rates. Epigenetics is th…