Erosive Hand Osteoarthritis

Existing disease-modifying and biologic treatments used in rheumatoid or psoriatic arthritis have had limited success in erosive hand osteoarthritis. Denosumab trial results support the possibility that structural modification is achievabl…

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Existing disease-modifying and biologic treatments used in rheumatoid or psoriatic arthritis have had limited success in erosive hand osteoarthritis. Denosumab trial results support the possibility that structural modification is achievable in erosive hand osteoarthritis. Erosive hand osteoarthritis is described as an inflammatory phenotype linked to pain and disease progression. Hand osteoarthritis is common and disabling, with fewer effective treatment options than hip or knee osteoarthritis.