ETC-1922159
The extracted text does not provide new dosing schedules or raw expression values for ETC-1922159 treatment. ETC-1922159 is treated as a PORCN-WNT inhibitor that down-regulates ASCL2 and many other genes in colorectal cancer cells. ETC-192…
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The extracted text does not provide new dosing schedules or raw expression values for ETC-1922159 treatment. ETC-1922159 is treated as a PORCN-WNT inhibitor that down-regulates ASCL2 and many other genes in colorectal cancer cells. ETC-1922159 is linked to reduced ASCL2, RNF43, and LGR5 expression through inhibition of PORCN-dependent WNT signaling. The study reanalyzes published colorectal cancer data generated after ETC-1922159 administration.