Excessive Fasting

The article says the fasting benefit-to-risk curve appears to peak around 14 to 18 hours for most adults. Fasting is presented as a hormetic stress that is beneficial at the right dose and harmful when excessive. Chronically elevated corti…

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The article says the fasting benefit-to-risk curve appears to peak around 14 to 18 hours for most adults. Fasting is presented as a hormetic stress that is beneficial at the right dose and harmful when excessive. Chronically elevated cortisol is presented as accelerating telomere shortening. Repeated daily fasting beyond 18 to 20 hours may keep cortisol elevated by making the body interpret the deficit as sustained survival stress.