Exposome

The exposome is broader than genetics and epigenetics. The exposome is the total set of exposures a person experiences across a lifetime. The exposome includes the full range of exposures across a person’s lifetime, not only industrial chemicals. The exposome refers to the cumulative environmental exposures a person experiences over a lifetime. The key challenge is identifying hidden variables that should have been measured. Researchers still need to identify which environmental exposures best predict early-onset colorectal cancer. The article frames exposomic scores as supported by prior youth-cohort work showing generalisability across suicide-attempt risk classification tasks. Cord blood testing has found numerous industrial chemicals in newborns. The study combines INE data with each participant's Google Takeout geospatial footprint to construct a personalised exposome. The exposome is the accumulation of all environmental exposures a person experiences over their lifetime, beginning before birth. Autoimmune disease is described as arising from interactions between genes and environmental exposures rather than genetics alone. In utero chemical exposure can affect multiple gene…