Fetal Growth Restriction

Normotensive FGR patients in cohort 2.3 require a lower DM199 dose intended to vasodilate uteroplacental vessels without causing maternal hypotension. FGR and pre-eclampsia share poor placental function from reduced placental perfusion as a common pathophysiological root. Fetal growth restriction most often arises from placental insufficiency and is a major independent risk factor for stillbirth and serious adverse perinatal outcomes.