Fusobacterium nucleatum

Colon cancer tissue removed surgically contains fusobacterium nucleatum at concentrations hundreds of times higher than expected. Animal studies provide direct causal evidence that fusobacterium nucleatum implanted in the colon causes colon cancer. Fusobacterium nucleatum is an oral pathogen that plays a significant role in colon cancer development. Once in circulation, fusobacterium nucleatum colonizes the colon and acts as a major trigger for cancer development. Fusobacterium nucleatum enters the bloodstream through micro traumas caused by routine dental activities such as flossing, brushing, and professional cleaning. Fusobacterium nucleatum is also implicated in breast cancer development.