G.1 Lineage
The study designated the Sierra Leone epidemic lineage as G.1, an alias of A.2.2.1. APOBEC3-like mutational enrichment in G.1 supports sustained human transmission rather than repeated zoonotic introductions. About 85% of reconstructed G.1…
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The study designated the Sierra Leone epidemic lineage as G.1, an alias of A.2.2.1. APOBEC3-like mutational enrichment in G.1 supports sustained human transmission rather than repeated zoonotic introductions. About 85% of reconstructed G.1 SNPs were consistent with APOBEC3 editing. Most analyzed Sierra Leone genomes belonged to clade IIb/sh2017. Sierra Leone's epidemic viruses formed a monophyletic group descended from lineage A.2.2.