Genetic Variation in Detoxification Enzymes

Cruciferous vegetables can partially compensate for genetic enzyme sluggishness by activating the genes that produce detoxification enzymes. Genetic enzyme deficiencies are not fixed — eating the right foods can compensate by upregulating gene expression. A significant portion of the population carries at least one detoxification enzyme mutation. DNA testing can reveal genetic mutations in detoxification enzyme genes that cause sluggish enzyme function. Enzyme gene mutations make individuals more susceptible to damage from specific toxins processed by that enzyme.