Gliotoxin
Gliotoxin inhibits phagocytosis in white blood cells and blocks the NF-kB pathway. Gliotoxin generates reactive oxygen species and produces several immunosuppressive effects. Gliotoxin is produced most commonly by Aspergillus fumigatus and…
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Gliotoxin inhibits phagocytosis in white blood cells and blocks the NF-kB pathway. Gliotoxin generates reactive oxygen species and produces several immunosuppressive effects. Gliotoxin is produced most commonly by Aspergillus fumigatus and also by Penicillium and Alternaria species. Gliotoxin exposure can come from contaminated foods and water-damaged buildings. The article presents avoidance as the primary treatment for gliotoxin exposure.