Glucocorticoid Use
Mean concomitant glucocorticoid dose decreased by 2 mg/day from baseline to month 24 during tofacitinib therapy. The percentage of patients using concomitant glucocorticoids fell from 62% at baseline to 46% at month 24. Increasing glucocor…
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Mean concomitant glucocorticoid dose decreased by 2 mg/day from baseline to month 24 during tofacitinib therapy. The percentage of patients using concomitant glucocorticoids fell from 62% at baseline to 46% at month 24. Increasing glucocorticoid dose during the study was associated with a higher likelihood of treatment step-up or switch, suggesting it functions as a marker of insufficient disease control.