Hayflick Limit

When telomerase-supported growth is supercritical, the Hayflick limit is infinite. Increasing chromosome number lowers the Hayflick limit in no-telomerase simulations. Increasing the minimum active telomere length lowers the Hayflick limit approximately linearly. The simulations define the Hayflick limit mathematically as the base-2 logarithm of the expected final population size. Without telomerase under default parameters, the simulated Hayflick limit is 45.9. The framework can estimate Hayflick limits when telomerase is absent or insufficient.