Histopathological Features

Basilar alignment was significantly more common in geriatric patients and supports histological diagnosis of mycosis fungoides. Geriatric patients had higher reported rates of several key histopathological features. Epidermotropism is a central diagnostic clue for mycosis fungoides but can also appear in inflammatory dermatoses. Epidermal atrophy was more frequent in geriatric patients but should not be used alone to diagnose mycosis fungoides. Papillary dermal fibrosis was more frequent in geriatric patients but may also be amplified by ageing skin and anatomical site.